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Identifying the Key Genes for Regeneration

9 minutes 54 seconds

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Illustration of a flat, narrow animal with a tube exiting from the bottom of the body toward the back. Caption: So what is the key to Planaria regeneration?

Identifying the key molecular players in planarian regeneration may offer clues into how the process may work in other species, including humans. HHMI investigator Alejandro Sánchez Alvarado and postdoctoral fellow Alice Accorsi use RNA-mediated genetic interference (RNAi) to silence different genes in planaria and determine how they affect regeneration.

Media Details

Runtime: 9 minutes 54 seconds

Topic: Science
Subtopic: Biology, Science Experiments, Science Methods
Grade/Interest Level: 10 - 12
Standards:

Release Year: 2017
Producer/Distributor: Howard Hughes Medical Institute
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Lab equipment in background with illustration of DNA strand, question marks, and an arrow pointing to the horn on a unicorn. Caption: We'd want to know what parts of the genome make the horn.

Lab equipment in background with illustration of connected neurons. Caption: glia activate and help fix the neurons

Still image from: 4 Awesome Discoveries You Probably Didn't Hear About This Week (Episode 36)

A caterpillar curled in a circle, mostly encased in a protective covering. Caption: Then the caterpillar goes to sleep.

Green foliage with a pink flower overlooks the shoreline. Spanish captions.

Closeup of a bright orange and blue tropical flower. Spanish captions.

A seal swimming underwater near the ocean floor. Caption: still remain to satisfy diurnal scavengers

A warthog with long tusks curving towards its body and leathery skin covered in mud. Caption: we can see that each has a beauty all its own.

Person driving a large piece of industrial farm equipment. Caption: towards managing agricultural systems

Still image from: All About Insects